Boehringer Ingelheim Exp

  • Boehringer Ingelheim has entered into a      collaboration and global license agreement for Bridge Biotherapeutics’s      autotaxin inhibitor BBT-877 to be developed for fibrosing interstitial      lung diseases including IPF

  • With this new partnership Boehringer Ingelheim      further expands its commitment to bring new treatments to patients with      fibrosing interstitial lung diseases including IPF

  • Bridge Biotherapeutics stands to receive up to      more than EUR 1.1 billion assuming all milestones are met

 

INGELHEIM, Germany & SEONGNAM, Korea -- (BUSINESS WIRE) --

Boehringer Ingelheim and Bridge Biotherapeutics Inc. today announced that they are entering into a new collaboration and license agreement with the goal of developing Bridge Biotherapeutics’s autotaxin inhibitor BBT-877 for patients with fibrosing interstitial lung diseases, including IPF. BBT-877 is currently in Phase I clinical studies and is anticipated to enter Phase II testing within the next 12 months.

Both companies will initially focus on developing the compound for the treatment of IPF, an area of high-unmet medical need and one of the key focus areas of Boehringer Ingelheim. Boehringer Ingelheim has developed OFEV® (nintedanib), an antifibrotic drug shown to slow disease progression by reducing lung function decline and currently approved for the treatment of IPF in more than 70 countries around the world including the US, the EU and Japan.

IPF is a rare, debilitating and fatal lung disease affecting approximately three million people worldwide. It causes progressive scarring of the lungs, resulting in continual and irreversible deterioration in lung function and breathing difficulties. BBT-877 inhibits autotaxin, an enzyme mediating a key pro-fibrotic event in multiple cell types. It has shown a promising safety and efficacy profile in pre-clinical models for fibrosing interstitial lung diseases and potential for combination with the current standard of care.

Michel Pairet, member of Boehringer Ingelheim’s Board of Managing Directors with responsibility for the company’s Innovation Unit said, “We look forward to working with the team at Bridge Biotherapeutics to develop a new treatment option for patients with IPF. This new collaboration complements our growing pipeline in fibrosing interstitial lung diseases and is a sign of our determination to bring the next generation of treatment options to these patients.”

“Bridge Biotherapeutics is pleased to partner with Boehringer Ingelheim, a recognized leader in IPF. The expertise of Boehringer Ingelheim will ensure that our novel therapeutic candidate can be developed to potentially address unmet medical needs of IPF patients worldwide,” said James Lee, CEO of Bridge Biotherapeutics.

“This is a transformational event for Bridge Biotherapeutics with a total potential value in excess of EUR 1.1 billion. It is a testament to the company’s excellence in the development of novel therapeutics for disease areas with high unmet medical need,” commented B. Chris Kim, PhD, a board member of Bridge Biotherapeutics based in Cambridge, Massachusetts.

Bridge Biotherapeutics will receive upfront and near term payments of EUR 45 million and is eligible to receive up to more than EUR 1.1billion in potential payments based upon the successful achievement of specified development, regulatory, and commercial milestones and staggered, up to double digit royalties.


相关推荐
新闻聚焦
猜你喜欢
热门推荐
  • 一只船教育最新消息让人兴奋,退费工作

      在我29岁的时候,我们发了产生报考消防工程师的想法,可能是当时的生活过得很艰辛,而在工作方面一直等不到领导的赏识......

    02-27    来源:阿里教育网

    分享
  • BOP 天堂鸟与大家逆境中冒险

      刚推出新歌《冒险岛》BOP天堂鸟早前于屯门一个篮球场及荃湾一个工作室拍摄MV,面对现时疫情问题他们表示担心,希望新歌......

    04-02    来源:文旅新闻网

    分享
  • 新沐教育最新消息:响应最新政策号召,

      今年毕业了,想考个教资,但是不知道怎么报名,自己也不会教资复习,所以想报个辅导机构来辅助我学习。通过同学的介绍......

    02-27    来源:网络

    分享
  • 践行新型智库建设精神 创建中国创新策划

      本网讯(通讯员 周乐玲) 2019年11月23日,在中国创意策划年会上,由《中国企业报》集团打造的中国策划行业的学术智库机构中国......

    02-02    来源:中华企业在线

    分享
  • 言成教育最新消息,平台为了保证退费工

      当今社会健康管理师可是一个非常热门的职业,有很多青年人都会趁自己有空闲的时间选择报考健康管理师的培训课程增加个......

    02-27    来源:阿里教育网

    分享
  • 学慧网最新消息:想办理退费,请一定要

      如今学慧网已经倒闭跑路了,所以在他家还有剩余学费的小伙伴们,一定要按照我所说的去办退费。 我在2022年7月份在京东上......

    02-27    来源:阿里教育网

    分享
  • 学霸君最新消息 2023年平台计划完成所有

      我家孩子在上高二时就受到了疫情的破坏,因为疫情到大力影响,学生只能在家上网课,可是通过一段时间在家的学习,孩子......

    02-27    来源:阿里教育网

    分享
  • 逸成教育最新消息:现在学费退费了,学

      逸成教育在互联网之上一直在说着,能够帮助我做好学历提升,可是当时我明确表示了自己没有那么多钱去学习,他们就开始......

    02-28    来源:阿里教育网

    分享
  • 兴为教育发布了退费的最新消息,学员们

      作为一个中年男人,平时的收入还没有一个保安的高,虽然我每天都很忙碌,但是也不知道具体忙的什么,钱也没有挣到,家......

    02-27    来源:阿里教育网

    分享
  • 学璐教育新一轮退费公告来了,退费工作

      我是一名全职宝妈,平时把所有的精力全部放在了孩子的身上,但是两个孩子的学习成绩都不怎么样,这让我非常失望,认为......

    02-27    来源:阿里教育网

    分享
返回列表
Ctrl+D 将本页面保存为书签,全面了解最新资讯,方便快捷。